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OCR: ulin, rise Plasma C-peptide levels, like those of i larger after B-cell stimulation but, because of pool size and slower turnover rate, larg common. fluctuations in plasma C-peptide are le ma Overnight fasting peripheral venous p. range C-peptide levels generally fall within tl evels, are 500-900pmol/l but, like plasma insulin s exercise, suppressed by prolonged fasting, vigor Le of and hypoglycaemia. Except in the prese urea endogenous hyperinsulinism, sulphor ne poisoning and some forms of autoimm trations hol/1 by hypoglycaemia, plasma C-peptide conc are invariably suppressed to below 300 sis of the hypoglycaemia (Fig. 20.17). This is the E us insulin hypoglycaemia test for endoger hyperinsulinism due to insulinoma.